Brno Ph.D. Talent
Brno Ph.D. Talent
GLP-1 RECEPTOR AGONISTS AS AN INNOVATIVE PHARMACOLOGICAL INTERVENTION FOR SUBSTANCE USE DISORDER
Lector: Jana Rudá Kučerová
Institution: Masaryk University, Faculty of Medicine
Field: Neuroscience
About the project
Substance use disorder lacks effective treatments. This project explores the potential of GLP-1 receptor agonists (GLP-1 RA), approved for diabetes and recently obesity treatment, to reduce methamphetamine intake and relapse. Using a rat operant model, we assess GLP-1 RA's effects on behavior, neuroimaging correlates, and neurotransmitters. Our findings could lead to repurposing GLP-1 RA as a treatment for methamphetamine use disorder, considering possible sex-specific differences.
Why science?
Simply, I love learning. Since childhood, I’ve been fascinated by understanding how things work. The brain is a complex, miraculous organ shaped by millions of years of evolution, bringing with it countless unanswered questions, such as how we think, perceive, decide, or find drive. As a neuroscientist, I see this endless complexity as both a challenge and an invitation to uncover the mechanisms behind the mind, emotion, perception, and behavior
What do I like most about Brno
Masaryk University with its excellent research opportunities and research network, the high number of international students in Brno, and its beautiful landscape.